WTF is the deal with the caronavirus?

ThePAMan

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Re: WTF is the deal with the caronavirus?

« Reply #2895 on: September 05, 2021, 09:48:19 AM »

Quote from: Mn on September 05, 2021, 09:44:11 AM

As in testing on "humanized mice" ?

On mice, lab rats, monkeys, whatever.

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Somewhere in Mn

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Re: WTF is the deal with the caronavirus?

« Reply #2896 on: September 05, 2021, 10:00:27 AM »

Quote from: ThePAMan on September 05, 2021, 09:37:55 AM

Don't they usually test this stuff on animals?

If the horse stuff works, get it out there.

We're working diligently on the $1000 version.

"Conclusions: Meta-analyses based on 18 randomized controlled treatment trials of ivermectin in COVID-19 have found large, statistically significant reductions in mortality, time to clinical recovery, and time to viral clearance. Furthermore, results from numerous controlled prophylaxis trials report significantly reduced risks of contracting COVID-19 with the regular use of ivermectin. Finally, the many examples of ivermectin distribution campaigns leading to rapid population-wide decreases in morbidity and mortality indicate that an oral agent effective in all phases of COVID-19 has been identified."
https://pubmed.ncbi.nlm.nih.gov/34375047/

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Somewhere in Mn

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Re: WTF is the deal with the caronavirus?

« Reply #2897 on: September 05, 2021, 10:18:22 AM »

Quote from: ThePAMan on September 05, 2021, 09:48:19 AM

On mice, lab rats, monkeys, whatever.

As in using mice to develop a coronavirus that can attack human airway cells ?
What could possibly go wrong ?

From 2015.
"In an article published in Nature Medicine1 on 9 November, scientists investigated a virus called SHC014, which is found in horseshoe bats in China. The researchers created a chimaeric virus, made up of a surface protein of SHC014 and the backbone of a SARS virus that had been adapted to grow in mice and to mimic human disease. The chimaera infected human airway cells — proving that the surface protein of SHC014 has the necessary structure to bind to a key receptor on the cells and to infect them. It also caused disease in mice, but did not kill them.

Although almost all coronaviruses isolated from bats have not been able to bind to the key human receptor, SHC014 is not the first that can do so. In 2013, researchers reported this ability for the first time in a different coronavirus isolated from the same bat population2."
https://www.nature.com/articles/nature.2015.18787

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alum74

2674
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Re: WTF is the deal with the caronavirus?

« Reply #2898 on: September 05, 2021, 12:22:55 PM »

Quote from: Mn on September 05, 2021, 10:00:27 AM

We're working diligently on the $1000 version.

"Conclusions: Meta-analyses based on 18 randomized controlled treatment trials of ivermectin in COVID-19 have found large, statistically significant reductions in mortality, time to clinical recovery, and time to viral clearance. Furthermore, results from numerous controlled prophylaxis trials report significantly reduced risks of contracting COVID-19 with the regular use of ivermectin. Finally, the many examples of ivermectin distribution campaigns leading to rapid population-wide decreases in morbidity and mortality indicate that an oral agent effective in all phases of COVID-19 has been identified."
https://pubmed.ncbi.nlm.nih.gov/34375047/

I hope the authors of the meta-analysis did not include this drug study in their investigation:

Flawed ivermectin preprint highlights challenges of COVID drug studies
“Before its withdrawal, the paper was viewed more than 150,000 times, cited more than 30 times and included in a number of meta-analyses that collect trial findings into a single, statistically weighted result.”

“The paper’s withdrawal is not the first scandal to dog studies of ivermectin and COVID-19. Andrew Hill [who studies repurposed drugs at the University of Liverpool, UK.] thinks many of the other ivermectin trial papers that he has scanned are likely to be flawed or statistically biased. Many rely on small sample sizes or were not randomized or well controlled, he says. And in 2020, an observational study of the drug was withdrawn after scientists raised concerns about it and a few other papers using data by the company Surgisphere that investigated a range of repurposed drugs against COVID-19.”
https://www.nature.com/articles/d41586-021-02081-w

But I agree we need more reliable data and support clinical trials that look at ivermectin’s effectiveness against COVID-19. The drug may make a difference in countries that don’t have widespread access to vaccines.

I would propose that a trial be performed in Oklahoma, stat.
Patients overdosing on ivermectin backing up rural Oklahoma hospitals, ambulances
https://kfor.com/news/local/patients-overdosing-on-ivermectin-backing-up-rural-oklahoma-hospitals-ambulances/

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Somewhere in Mn

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Re: WTF is the deal with the caronavirus?

« Reply #2899 on: September 05, 2021, 12:26:08 PM »

January in Oklahoma

September in Oklahoma

The doc's story

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fucking

3174
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Who Doesn't?

Re: WTF is the deal with the caronavirus?

« Reply #2900 on: September 05, 2021, 12:50:47 PM »

What does a statement from Northeastern Health System have to do with "eastern and southeastern Oklahoma hospitals?"

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alum74

2674
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Re: WTF is the deal with the caronavirus?

« Reply #2901 on: September 05, 2021, 02:20:10 PM »

“Do your research!”

A panel from the National Institutes of Health found “insufficient evidence” for or against using ivermectin for Covid-19. “Results from adequately powered, well-designed, and well-conducted clinical trials are needed to provide more specific, evidence-based guidance on the role of ivermectin in the treatment of COVID-19.”
https://www.covid19treatmentguidelines.nih.gov/therapies/antiviral-therapy/ivermectin/

The American Medical Association has called for an “immediate end” to using, prescribing and dispensing the drug to prevent or treat COVID-19, outside of a clinical trial.
https://www.ashp.org/News/2021/09/01/ama-apha-ashp-call-for-end-to-ivermectin-to-prevent-or-treat-covid-19?loginreturnUrl=SSOCheckOnly

U.S. Food and Drug Administration has warned that taking large doses of the drug can cause serious harm, including nausea, vomiting, diarrhea, seizures, delirium and death.
https://www.fda.gov/consumers/consumer-updates/why-you-should-not-use-ivermectin-treat-or-prevent-covid-19

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ThePAMan

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Re: WTF is the deal with the caronavirus?

« Reply #2902 on: September 05, 2021, 02:31:38 PM »

From what I read, the story and claims about the OK hospitals could not be substantiated.

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Mark Carman: "The Whitlock!...Caleb Williams failed Wayne Whitlock." Been told I need to take my dick out my mouth so maybe I "wont [sic] sound like such a fucking faggot all the time[.]"

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murphstahoe

8168
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Re: WTF is the deal with the caronavirus?

« Reply #2903 on: September 05, 2021, 03:15:47 PM »

this whole thing is like I don't have to quit smoking because lung transplants

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alum74

2674
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Re: WTF is the deal with the caronavirus?

« Reply #2904 on: September 05, 2021, 03:34:45 PM »

Quote from: ThePAMan on September 05, 2021, 02:31:38 PM

From what I read, the story and claims about the OK hospitals could not be substantiated.

Agree. Two of the regional health systems have issued statements to the contrary. The third system where he may have worked has not yet issued a statement.
www.nwahomepage.com/news/around-the-region/oklahoma-hospitals-respond-after-doctor-says-ivermectin-overdoses-backing-up-emergency-rooms/

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Somewhere in Mn

12634
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Re: WTF is the deal with the caronavirus?

« Reply #2905 on: September 06, 2021, 06:08:42 PM »

I read this one, dated Aug 3, this morning.
Now I understand the Oklahoma ER bs story, and it's purpose. And why Twitter hasn't taken the story down.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383101/

"We believe that the evidence to date supports the worldwide extension of IVM treatments for COVID-19, complementary to immunizations. The indicated biological mechanism of IVM, competitive binding with SARS-CoV-2 spike protein, is likely non-epitope specific, as reviewed [8], possibly yielding full efficacy against emerging viral mutant strains. IVM has been safely used in 3.7 billion doses since 1987, well tolerated even at much greater than standard doses [34,35] and used without serious AEs in the three high-dose COVID-19 treatment studies noted above [34,36,37]. In the current international emergency of COVID-19, with mutant viral strains, vaccination refusals and potentially waning immunities over months presenting new challenges, IVM can be an effective component of the mix of therapeutics deployed against this pandemic."

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ThePAMan

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Re: WTF is the deal with the caronavirus?

« Reply #2906 on: September 06, 2021, 06:57:58 PM »

Ok, I'll bite. What was the purpose of the BS OK story?

They tested it on golden hamsters!

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Mark Carman: "The Whitlock!...Caleb Williams failed Wayne Whitlock." Been told I need to take my dick out my mouth so maybe I "wont [sic] sound like such a fucking faggot all the time[.]"

Tempo: "PAMan is a pot stirrer and agent provocateur"

Somewhere in Mn

12634
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Re: WTF is the deal with the caronavirus?

« Reply #2907 on: September 06, 2021, 07:37:50 PM »

Quote from: ThePAMan on September 06, 2021, 06:57:58 PM

Ok, I'll bite. What was the purpose of the BS OK story?
Quote from: ThePAMan on September 06, 2021, 06:57:58 PM
Ok, I'll bite. What was the purpose of the BS OK story?

They tested it on golden hamsters!

They tested it on golden hamsters!

These stories always have a purpose.
Everybody who saw it will think it's true.
Until proven otherwise. How many still think its true ?
Rolling Stone was not the only outlet that promoted it. Not by any means.
Get your booster. Plans are in motion for a Sept 20 launch. Ivermectin will put you in the ER. Get your booster.

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ThePAMan

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Re: WTF is the deal with the caronavirus?

« Reply #2908 on: September 06, 2021, 07:40:42 PM »

The vaccine manufacturers generated the story?

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Mark Carman: "The Whitlock!...Caleb Williams failed Wayne Whitlock." Been told I need to take my dick out my mouth so maybe I "wont [sic] sound like such a fucking faggot all the time[.]"

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Somewhere in Mn

12634
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Re: WTF is the deal with the caronavirus?

« Reply #2909 on: September 06, 2021, 07:47:33 PM »

Quote from: ThePAMan on September 06, 2021, 07:40:42 PM

The vaccine manufacturers generated the story?

You're a lawyer, correct ?
FOIA the doc's emails.
I have a hard time believing someone would come up with a hare-brained story like this without some incentives.
People lined up with gun shot wounds to get in a rural OK ER. 🤣🤣🤣🤣🤣
If they would have picked Chicago it might have been a better pick, but where are you going to find rural hicks taking horse ivermectin in Englewood ?

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