The vaccine results in an inflammatory response and essentially equal immunity between those who develop myocarditis and those who don't.
The ones who develop myocarditis have spike proteins running around free in their system. The ones who don't develop myocarditis don't have free spike proteins.
The presence of free spike proteins may be predictive for myocarditis or a heart attack, or explain a heart attack or myocarditis that has already occurred.
More from the authors of the study:
“'The risk of developing severe disease from acute infection significantly outweighs this rare risk,' stated Lael Yonker, pediatric pulmonary medicine specialist at Mass General for Children, and first author of the study. 'While this finding helps us better understand this potential complication, it does not alter the risk benefit ratio of receiving the COVID vaccines. The incidence of myocarditis and other heart-related complications among children infected with SARS-CoV-2 is much higher than the risk of post-vaccination myocarditis.'”
"The authors also noted it remains unclear whether the circulating spike protein was the cause of the myocarditis observed in these patients. Rare cases of myocarditis can occur after receiving vaccines for other conditions such as smallpox, so the spike protein could have been a biomarker of underlying immune dysregulation leading to the symptoms."
“'This was a precious sample set because these cases are so rare,' stated co-corresponding author David Walt, professor in the Brigham’s Department of Pathology. 'We studied them in great depth, which led to an interesting finding that could guide treatment strategies to reverse post-vaccine myocarditis.'”
"Previously suggested causes for post-vaccine myocarditis include aberrant immune responses to the vaccine, the production of autoantibodies, or potentially spike protein mimicking self-antigens, leading the immune system to attack heart tissue. Another factor at play is that myocarditis affects young men more than young women, which could be explained with hormonal mechanisms. Nonetheless, Yonker and Walt et al. found circulating spike protein in female patients as much as in male patients."
"The authors acknowledged limitations in their study, with a myocarditis group sample size of just 16. However, given the rarity of these cases, it was to be expected."
"In any case, the study continues to hammer home the point that vaccination for COVID-19 carries much fewer risks than infection by the virus, including for adolescents and young adults."
“'In most cases, post-vaccination myocarditis is mild and self-resolving,' said Yonker. 'But new insights about its cause could further help us to improve patients’ symptoms or prevent this complication from occurring.'”
https://www.insideprecisionmedicine.com/topics/patient-care/coronavirus/rare-covid-19-vaccine-complication-linked-to-circulating-spike-protein-in-blood/
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