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WTF is the deal with the caronavirus?

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Somewhere in Mn

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Re: WTF is the deal with the caronavirus?
« Reply #3810 on: December 23, 2021, 06:19:58 PM »
Quote from: ThePAMan on December 23, 2021, 06:03:33 PM
[Illini] Can the government NIH be trusted?[Golf]
The researchers with data ? Or the beaurocrats ?
It's an interesting article.
« Last Edit: December 23, 2021, 06:25:04 PM by Mn »
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ThePAMan

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Re: WTF is the deal with the caronavirus?
« Reply #3811 on: December 23, 2021, 06:24:12 PM »
Quote from: Mn on December 23, 2021, 06:19:58 PM
The researchers with data ? Or the beaurocrats ?

[QAnon]Like that matters? It is all about control![97]
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ILLove1997

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Re: WTF is the deal with the caronavirus?
« Reply #3812 on: December 23, 2021, 06:47:56 PM »
Quote from: ThePAMan on December 23, 2021, 01:25:26 PM
GMAFB. You are purportedly smarter than JizzJerkoff. Mandating you wear a fucking mask at a shopping mall does not keep people subserviant so they don't vote you out. That is just fucking stupid.

You steal Gelato's stash?

how many state governors have willingly relinquished their emergency powers?
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alum74

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Re: WTF is the deal with the caronavirus?
« Reply #3813 on: December 23, 2021, 07:14:58 PM »
Quote from: Mn on December 23, 2021, 05:54:49 PM
Other than your April and June articles, I might skip your Popular Science article by MK Menon and go with something more current from the NIH......
Not that there's anything wrong with Yahoo Life or Today's Parent.



" Both datasets show a strong correlation between the death rate caused by SARS-CoV-2 and the vitamin D blood level. At a threshold level of 30 ng/mL, mortality decreases considerably. In addition, our analysis shows that the correlation for the combined datasets intersects the axis at approximately 50 ng/mL, which suggests that this vitamin D3 blood level may prevent any excess mortality. "
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541492/
COVID-19 Mortality Risk Correlates Inversely with Vitamin D3 Status, and a Mortality Rate Close to Zero Could Theoretically Be Achieved at 50 ng/mL 25(OH)D3: Results of a Systematic Review and Meta-Analysis

From the study you cited:
“Although there exists very broad data-based support for the protective effect of vitamin D against severe SARS-CoV-2 infections, we strongly recommend initiating well-designed observational studies as mentioned and/or double-blind randomized controlled trials (RCTs) to convince the medical community and the health authorities that vitamin D testing and supplementation are needed to avoid fatal breakthrough infections and to be prepared for new dangerous mutations.”

Like I said earlier, I think the jury is still out, plus NIH has not updated it current position that “there is insufficient evidence to recommend either for or against the use of vitamin D for the prevention or treatment of COVID-19.”    . 

Let’s wait for the results from well-designed studies that are currently underway, especially double-blind, placebo-controlled randomized trials.  Further research is also needed to determine appropriate dose, duration and delivery mode for vitamin D.   

Meanwhile, I’ll keep taking the vitamin D supplements that my doctor recommended. 

P.S.  I’m not a big fan of meta-analyses because of quality control issues.   Nevertheless, here’s a recent one that found "vitamin D deficiency or insufficiency was not significantly linked to susceptibility to COVID-19 infection or its associated death."
https://nutritionj.biomedcentral.com/articles/10.1186/s12937-021-00744-y#citeas
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Somewhere in Mn

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Re: WTF is the deal with the caronavirus?
« Reply #3814 on: December 23, 2021, 07:15:49 PM »
Quote from: ILLove1997 on December 23, 2021, 06:47:56 PM
how many state governors have willingly relinquished their emergency powers?
Oregon just extended hers til June.
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Somewhere in Mn

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Re: WTF is the deal with the caronavirus?
« Reply #3815 on: December 23, 2021, 07:53:50 PM »
Quote from: alum74 on December 23, 2021, 07:14:58 PM
From the study you cited:
“Although there exists very broad data-based support for the protective effect of vitamin D against severe SARS-CoV-2 infections, we strongly recommend initiating well-designed observational studies as mentioned and/or double-blind randomized controlled trials (RCTs) to convince the medical community and the health authorities that vitamin D testing and supplementation are needed to avoid fatal breakthrough infections and to be prepared for new dangerous mutations.”

Like I said earlier, I think the jury is still out, plus NIH has not updated it current position that “there is insufficient evidence to recommend either for or against the use of vitamin D for the prevention or treatment of COVID-19.”    . 

Let’s wait for the results from well-designed studies that are currently underway, especially double-blind, placebo-controlled randomized trials.  Further research is also needed to determine appropriate dose, duration and delivery mode for vitamin D.   

Meanwhile, I’ll keep taking the vitamin D supplements that my doctor recommended. 

P.S.  I’m not a big fan of meta-analyses because of quality control issues.   Nevertheless, here’s a recent one that found "vitamin D deficiency or insufficiency was not significantly linked to susceptibility to COVID-19 infection or its associated death."
https://nutritionj.biomedcentral.com/articles/10.1186/s12937-021-00744-y#citeas

And from article 22 that they cite
"The final analysis included 144 patients with confirmed COVID-19 (median age, 66 years; 64 [44.4%] male). Overall mortality was 18%, whereas patients with 25(OH)D levels of 30 ng/mL (to convert to nmol/L, multiply by 2.496) and higher had lower rates of mortality compared with those with 25(OH)D levels below 30 ng/mL (9.2% vs 25.3%; P=.02). In the adjusted multivariable analyses, 25(OH)D as a continuous variable was independently significantly associated with lower in-hospital mortality (odds ratio, 0.94; 95% CI, 0.90 to 0.98; P=.007) and need for invasive mechanical ventilation (odds ratio, 0.96; 95% CI, 0.93 to 0.99; P=.01)."
And from article 31
"Bolus vitamin D3 supplementation during or just before COVID-19 was associated with less severe COVID-19 in frail elderly.
Bolus vitamin D3 supplementation during or just before COVID-19 was associated with better survival rate in frail elderly."

Vitamin D can be prescribed by any doc. The people dying every day probably dont care much about how long the jury wants to deliberate.
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Reacher

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Re: WTF is the deal with the caronavirus?
« Reply #3816 on: December 23, 2021, 08:05:51 PM »
Quote from: ILLove1997 on December 23, 2021, 11:29:47 AM
if you're over 50 get the shot

if you're not and in good health, don't bother

why is that an antivaxxer take lol

Why not get the shot if you’re 40 and in “good shape?”
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ThePAMan

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Re: WTF is the deal with the caronavirus?
« Reply #3817 on: December 23, 2021, 08:35:57 PM »
Quote from: Mn on December 23, 2021, 07:15:49 PM
Oregon just extended hers til June.

Maybe the Sandinistas have taken over in Oregon.
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ThePAMan

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Re: WTF is the deal with the caronavirus?
« Reply #3818 on: December 23, 2021, 08:37:43 PM »
Quote from: ILLove1997 on December 23, 2021, 06:47:56 PM
how many state governors have willingly relinquished their emergency powers?

I believe we are still in this, don't you think?
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alum74

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Re: WTF is the deal with the caronavirus?
« Reply #3819 on: December 23, 2021, 08:47:19 PM »
Quote from: Mn on December 23, 2021, 07:53:50 PM
And from article 22 that they cite
"The final analysis included 144 patients with confirmed COVID-19 (median age, 66 years; 64 [44.4%] male). Overall mortality was 18%, whereas patients with 25(OH)D levels of 30 ng/mL (to convert to nmol/L, multiply by 2.496) and higher had lower rates of mortality compared with those with 25(OH)D levels below 30 ng/mL (9.2% vs 25.3%; P=.02). In the adjusted multivariable analyses, 25(OH)D as a continuous variable was independently significantly associated with lower in-hospital mortality (odds ratio, 0.94; 95% CI, 0.90 to 0.98; P=.007) and need for invasive mechanical ventilation (odds ratio, 0.96; 95% CI, 0.93 to 0.99; P=.01)."
And from article 31
"Bolus vitamin D3 supplementation during or just before COVID-19 was associated with less severe COVID-19 in frail elderly.
Bolus vitamin D3 supplementation during or just before COVID-19 was associated with better survival rate in frail elderly."

Vitamin D can be prescribed by any doc. The people dying every day probably dont care much about how long the jury wants to deliberate.

I didn't need a prescription for vitamin D.  My doctor gave me a recommendation on the brand and dosage.  I purchased the supplements both online and locally.

As for the people who are dying, I wouldn't want to speculate on what they are thinking.
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Somewhere in Mn

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Re: WTF is the deal with the caronavirus?
« Reply #3820 on: December 23, 2021, 09:28:43 PM »
Quote from: alum74 on December 23, 2021, 08:47:19 PM
I didn't need a prescription for vitamin D.  My doctor gave me a recommendation on the brand and dosage.  I purchased the supplements both online and locally.

As for the people who are dying, I wouldn't want to speculate on what they are thinking.
Anything to get to 30ng/ml or higher would most likely require 50,000 unit dosing, which requires a prescription. Over the counter formulations can probably get to 20-25 ng/ml depending on the starting blood levels.
Dosing is done with blood work.
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Custard

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Re: WTF is the deal with the caronavirus?
« Reply #3821 on: December 23, 2021, 10:07:39 PM »
So we had time for multiple companies to develop vaccines, test them for efficacy, acquire emergency use approval, and administer them for a full year…but we must take a years long wait and see approach on the efficacy of readily available Vitamin D, which was being suggested almost from the start as a potential therapeutic. 🤷🏻‍♂️

I’m sure it has nothing to do with the fact that Vitamin D3 is dirt cheap, readily available, and that the wrong people were touting it from the get go.

If there is actually anything to this, it is going to take an absolute mountain of overwhelming evidence that D3 has therapeutic benefit for the millions upon millions of people who are entirely invested in deifying the vaccines/CDC to even begin to acknowledge that they openly vilified people for championing lifesaving tools we already had in our arsenal.

The skeptic in me can think of hundreds of billions of reasons why large scale studies into D3 have not been conducted in earnest, or why the results of any small scale preliminary trials will be obfuscated for as long as possible.

But then I remember the federal government and huge multinational corporations have an impeccable track record of transparently doing what’s right by us, and then I feel silly for even bringing it up.

« Last Edit: December 23, 2021, 10:16:01 PM by Custard »
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Re: WTF is the deal with the caronavirus?
« Reply #3822 on: December 23, 2021, 10:31:13 PM »
When people realize it can rebuild destroyed lung tissue, the COPD industrial complex finna be pissed.
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ThePAMan

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Re: WTF is the deal with the caronavirus?
« Reply #3823 on: December 23, 2021, 10:49:53 PM »
Who said it was going to take years?
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ILLove1997

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Re: WTF is the deal with the caronavirus?
« Reply #3824 on: December 23, 2021, 11:11:43 PM »
Quote from: Tempo34 on December 23, 2021, 08:05:51 PM
Why not get the shot if you’re 40 and in “good shape?”

Because the odds of a bad side effect are greater than the likely effects of covid
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